Future Goals: To secure a position where I can expand my academic and research experience, and to contribute to solving problems that stand in the way of the creation of pervasive technologies. Namely, I'm interested in Computer Aided Protein Engineering & Design, especially as applied to Viral Vectors or Gene Editing Technology. Ideally whatever position I might secure will utilize my pre-existing academic background in physics and programing.
Second Rotation (Durrant Lab): Pocket Conformation Progress Coordinate for WestPA: The goal of this rotation was to establish a progress coordinate representative of pocket conformation (size and shape) to allow for efficient sampling using the Weighted Ensemble path sampling algorithm via WestPA and NAMD Molecular Dynamics. While this project was successful in establishing the aforementioned progress coordinate, a production run was not complete before the rotation's end.
First Rotation (Chong Lab): Using WestPA to Characterize Foldon Monomer Folding: The goal of this rotation was to characterize the Foldon Trimerization Domain (1RFO)'s folding and unfolding processes using the Weighted Ensemble path sampling algorithm via WestPA and AMBER Molecular Dynamics. Specifically, the goal was to perform equilibrium simulations to determine the general characteristics of the system then use that information to run steady-state simulations capable of more efficiently sampling the kinetics. While much progress was made in setting up a WestPA Simulation, production runs were not complete before the rotation's end. As such, this project was not completed.
Collagen-Encapsulation Drug Delivery System: The project focused on the creation and optimization of collagen nano-particles that encapsulate various drugs of interest. The primary goal was to characterize the particles' functionality as a drug delivery system (size, dispersity, spontaneous release, storage, toxicity, etc.)Experience & Training:
High-Throughput SPR Sensors for Matrix Metalloproteinases: This project focused on using Surface Plasmon Resonance with the degradation of collagen to create a collagenase sensor. The aim was to get quantitative measurements of collagenase concentrations based off the kinetic association constants and an SPR degradation formula.Experience & Training:
|2017-????||Graduate Student at the University of Pittsburgh's Molecular Biophysics and Structural Biology Graduate Program.|
|2015-2017||B.S. in NanoScience |
College of Nanoscale Science and Engineering (CNSE), Albany NY
|2012-2014||A.S. in Science and Mathematics |
Northwest Missouri State University, Maryville MO
|Biology & Proteins||Math & Programing||Physics|
|Microbiology||Programing I & II||Intro. to Quantum Theory|
|Biochemistry||Scientific Computing||Quantum Origins of Mat. Prop.|
|Nanobiomanufacturing||Multi-Variable Calculus||Advanced Circuits|
|Nanobio. for Nanotech. Apps.||Linear Algebra||Structure of Matter|
|Soft Matter||Analysis for Applications||NanoLab I & II|
|Nano. Chem. and Bio. Sensors||Thermo. & Stat. Mechanics||Nanoscale Design|
|Organic Chemistry I||Nanoscale Electronic Devices|
|Foundations of Biomedical Science||Charged Particle Optics|
|Molecular Biophysics I||Advanced Phys/Chem Concepts|